If your a Mac OS X Leopard or Tiger user and want to use Wine you can find precompiled binary downloads with FreeType 2.3.5, FontForge py25-20071210, and Liberation Fonts here.

From the site: Random Tidbits of Information

Instead of having to run a script after installing Darwine to set fonts up, I’ve packaged everything into a .pkg that installs the latest version of Darwine to /Applications/Darwine, the latest versions of FontForge and FreeType to their proper places in /usr, and Liberation fonts to ~/.wine/drive_c/windows/fonts.

If you’re updating to a newer version of Darwine, you don’t need to reinstall FontForge or FreeType and can deselect those packages.

If you install Liberation fonts, the installer renames your current ~/.wine to ~/.wine-xxxxxx where xxxxxx is a random set of alphanumeric characters. If you want to restore your old ~/.wine dir, you should delete, rename or move ~/.wine somewhere else and then rename ~/.wine-xxxxx to ~/.wine.

The installer is still in beta, but it installs everything to the proper places and nothing major should change between now and whenever it’s not beta. It is Leopard-only.

It is and will always be Intel only. Wine, and by extension, Darwine, does not do any emulating. It is an API layer. For it to run on PPC, it would need to emulate some x86 stuff. This is what Darwine originally attempted to do in combination with QEMU, however it is no longer necessary with the switch to Intel.